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Shawna L Stratton Selected Research

Biotin deficiency

9/2012Measurement of acylcarnitine substrate to product ratios specific to biotin-dependent carboxylases offers a combination of indicators of biotin status in humans.
1/2012Marginal biotin deficiency can be induced experimentally in humans using a cost-effective outpatient design.
11/2011Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans.
3/2011Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.
12/2010Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.
11/2010Quantitative measurement of urinary excretion of 3-hydroxyisovaleryl carnitine by LC-MS/MS as an indicator of biotin status in humans.
5/2010Quantitative measurement of plasma 3-hydroxyisovaleryl carnitine by LC-MS/MS as a novel biomarker of biotin status in humans.
8/2006Lymphocyte propionyl-CoA carboxylase and its activation by biotin are sensitive indicators of marginal biotin deficiency in humans.
5/2005Marginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylases.
1/2005Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood.
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Shawna L Stratton Research Topics

Disease

11Biotin deficiency
09/2012 - 10/2004
1Uterine Cervical Dysplasia
10/2015
1Congenital Abnormalities (Deformity)
05/2005

Drug/Important Bio-Agent (IBA)

7Biotin (Vitamin H)FDA Link
09/2012 - 10/2004
5Indicators and Reagents (Reagents)IBA
10/2015 - 01/2005
4Carnitine (L-Carnitine)FDA LinkGeneric
01/2012 - 12/2010
3beta-hydroxyisovaleric acid (beta-hydroxy-beta-methylbutyrate)IBA
01/2012 - 08/2006
3Propionyl-Coenzyme A Carboxylase (Propionyl CoA Carboxylase)IBA
01/2012 - 08/2006
2Biomarkers (Surrogate Marker)IBA
11/2010 - 05/2010
1VaccinesIBA
10/2015
1Vaccine AdjuvantsIBA
10/2015
1Peptides (Polypeptides)IBA
10/2015
1Acyl Coenzyme A (Acyl CoA)IBA
09/2012
1AvidinIBA
01/2012
1Leucine (L-Leucine)FDA Link
11/2011
1CreatinineIBA
03/2011
1EnzymesIBA
12/2010
1TeratogensIBA
08/2006
1Ligases (Synthetase)IBA
05/2005
1biotin transporterIBA
01/2005